- Measures
- Resting mV̇O₂, rate constant k, time constant τ, exercise stimulus
- Input
- Artinis Oxysoft exports; Train.Red FYER exports
- Runs on
- Windows 10 / 11, 64-bit
- Version
- 1.2.0, September 2026
- Licence
- Proprietary, free of charge for research and education
MCMITO
Raw repeated occlusion recordings to resting mV̇O₂, rate constant and time constant, in one rapid, auditable workflow.
MCMITO imports raw NIRS recordings from repeated arterial occlusion protocols and delivers the key metrics of muscle oxidative capacity within minutes: resting muscle oxygen consumption (mV̇O₂), the recovery rate constant (k) and the time constant (τ). Occlusions are detected automatically with a confidence score you can accept or adjust, blood volume correction and physiological calibration are applied, and the recovery of mV̇O₂ is fitted with standard errors and fit quality reported. The exercise stimulus preceding each occlusion set is also quantified, so you can confirm the protocol delivered the intended intensity, and the analysis adapts to a range of protocol designs and occlusion sequences. Every per-occlusion slope, exclusion and fit stays visible and exportable, with results going out as Excel workbooks and PDF reports.
Not a medical device. Intended for research and educational use only.
Created byDr Chris McManus, University of Essex
Cite asMcManus, C. (2026). MCMITO: Near-infrared spectroscopy analysis of skeletal-muscle mitochondrial oxidative capacity (Version 1.2.0) [Computer software]. Zenodo.